How are Bovine Nucleus Pulposus Cell Populations Affected by Cell Isolation Methods?
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چکیده
منابع مشابه
Nucleus pulposus cell-matrix interactions with laminins.
The cells of the nucleus pulposus (NP) region of the intervertebral disc play a critical role in this tissue's generation and maintenance, and alterations in NP cell viability, metabolism, and phenotype with aging may be key contributors to progressive disc degeneration. Relatively little is understood about the phenotype of NP cells, including their cell-matrix interactions which may modulate ...
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pulposus phenotype in human MSCs +Purmessur, D; Godburn K; Abbott, RD: Schek RM; Iatridis JC +University of Vermont, Burlington VT Senior author [email protected] INTRODUCTION Mesenchymal stem cells (MSCs) are an attractive cell source for IVD repair, yet the means of differentiating these cells to a nucleus pulposus (NP) phenotype is not clear and an area of high priority. Notochordal cel...
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The nucleus pulposus (NP) of the intervertebral disc functions to provide compressive load support in the spine, and contains cells that play a critical role in the generation and maintenance of this tissue. The NP cell population undergoes significant morphological and phenotypic changes during maturation and aging, transitioning from large, vacuolated immature cells arranged in cell clusters ...
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ژورنال
عنوان ژورنال: Global Spine Journal
سال: 2012
ISSN: 2192-5682,2192-5690
DOI: 10.1055/s-0032-1319959